By Jean Louis Guénet,Fernando Benavides,Jean-Jacques Panthier,Xavier Montagutelli
This publication, written via skilled geneticists, covers subject matters starting from the common historical past of the mouse species, its dealing with and replica within the laboratory, and its classical genetics and cytogenetics, to trendy concerns together with the research of the transcriptome, the parental imprinting and X-chromosome inactivation. The thoughts for developing all kinds of mutations, both through genetic engineering or by utilizing mutagens, also are reviewed and mentioned intimately. ultimately, a final bankruptcy outlines the method used for the research of complicated or quantitative traits.
The authors additionally speak about the significance of actual phenotyping, that is now played within the mouse clinics tested around the world and determine the bounds of the mouse version, which lower than definite conditions can fail to offer the phenotype anticipated from the cognate within the human version. for every bankruptcy an up to date checklist of pertinent references is equipped.
In brief, this ebook bargains a necessary source for all scientists who use or plan to take advantage of mice of their research.
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Genetics of the Mouse by Jean Louis Guénet,Fernando Benavides,Jean-Jacques Panthier,Xavier Montagutelli
by Ronald
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