By Onkar N. Tripathi,Ursula Ravens,Michael C. Sanguinetti
Pathological center rhythms are a huge health and wellbeing factor. during this booklet specialists from numerous fields supply an incredible context for knowing the advanced molecular and mobile mechanisms that underlie general and pathophysiological cardiac rhythms.
Individual chapters conceal an entire diversity of issues, together with the ionic foundation of pacemaking, the position of particular channels and transporters in sinoatrial node pacemaking, altered intracellular Ca2+ dealing with in line with illness, desktop modeling of the motion potentials of pacemaker and dealing cardiomyocytes, genetic and molecular foundation of inherited arrhythmias and a evaluate of confirmed and novel antiarrhythmic brokers. as a result key significance of the really expert pacemaker cells and tissue (sinoatrial and atrioventricular nodes) in conserving center expense and rhythm, exact emphasis is put on the odd electrophysiology of those cells.
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Heart Rate and Rhythm: Molecular Basis, Pharmacological Modulation and Clinical Implications by Onkar N. Tripathi,Ursula Ravens,Michael C. Sanguinetti
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